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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2130
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apoa1
Name: apolipoprotein A1
Acc ID: CHEBI:82195
Term: Clofop
Definition: An aromatic ether that has formula C15H13ClO4.
Chemical ID: MESH:C006012
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apoa1decreases expressionEXP 6480464CTDfenofibric acid results in decreased expression of APOA1 mRNAPMID:7556148
Apoa1multiple interactionsEXP 6480464CTD[fenofibric acid co-treated with Dexamethasone] results in increased expression of APOA1 mRNA; [fenofibric acid co-treated with Tretinoin] results in increased expression of APOA1 mRNA; fenofibric acid inhibits the reaction [Dexamethasone results in increased expression of APOA1 mRNA]; fenofibric acid inhibits the reaction [Tretinoin results in increased expression of APOA1 mRNA]PMID:7556148
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