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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2744 Species: Rattus norvegicus RGD Object: Gene Symbol: Grm3 Name: glutamate receptor, metabotropic 3

Acc ID: CHEBI:8207 Term: (+)-pilocarpine Definition: A pilocarpine that has formula C11H16N2O2. CasRN: 92-13-7 Chemical ID: MESH:D010862

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	EXP		6480464	CTD	Pilocarpine results in decreased expression of GRM3 mRNA	PMID:18804094 PMID:18585369
decreases expression	EXP		6480464	CTD	Pilocarpine results in decreased expression of GRM3 protein	PMID:18804094 PMID:16793029
decreases expression	EXP		6480464	CTD	Pilocarpine results in decreased expression of GRM3 protein	PMID:16793029 PMID:18804094
decreases expression	EXP		6480464	CTD	Pilocarpine results in decreased expression of GRM3 mRNA	PMID:18585369 PMID:18804094