GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Drd2 | decreases activity | EXP | | 6480464 | CTD | Pilocarpine results in decreased activity of DRD2 protein | PMID:15876489 | Drd2 | decreases expression | EXP | | 6480464 | CTD | Pilocarpine results in decreased expression of DRD2 protein | PMID:15876489 | Drd2 | decreases response to substance | EXP | | 6480464 | CTD | DRD2 protein results in decreased susceptibility to Pilocarpine | PMID:1365435 | Drd2 | multiple interactions | EXP | | 6480464 | CTD | [[Remoxipride results in decreased activity of DRD2 protein] co-treated with [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide results in decreased activity of HTR1A protein]] results in increased susceptibility to Pilocarpine; [Remoxipride results in decreased activity of DRD2 protein] inhibits the reaction [Dopamine results in decreased susceptibility to Pilocarpine]; Pilocarpine inhibits the reaction [Spiperone binds to DRD2 protein]; Pilocarpine promotes the reaction [Spiperone binds to DRD2 protein] | PMID:14559291 PMID:15140183 PMID:16137708 | Drd2 | decreases response to substance | ISO | Drd2 (Mus musculus) | 6480464 | CTD | DRD2 protein results in decreased susceptibility to Pilocarpine | PMID:11860278 | |
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