GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Drd1 | decreases expression | EXP | | 6480464 | CTD | Pilocarpine results in decreased expression of DRD1 protein | PMID:15876489 | Drd1 | increases expression | EXP | | 6480464 | CTD | Pilocarpine results in increased expression of DRD1 mRNA | PMID:14656328 | Drd1 | increases response to substance | EXP | | 6480464 | CTD | DRD1 protein results in increased susceptibility to Pilocarpine | PMID:1365435 | Drd1 | multiple interactions | EXP | | 6480464 | CTD | Pilocarpine inhibits the reaction [SCH 23390 binds to DRD1 protein] | PMID:16137708 | Drd1 | multiple interactions | ISO | Drd1 (Mus musculus) | 6480464 | CTD | [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein] which results in increased susceptibility to Pilocarpine; [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Dizocilpine Maleate] co-treated with [1-hydroxy-3-amino-2-pyrrolidone results in increased activity of DRD1 protein]] results in increased susceptibility to Pilocarpine | PMID:7906944 | | ||||||||||||||||||||||
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