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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310075
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vnn1
Name: vanin 1
Acc ID: CHEBI:81975
Term: spirotetramat
Definition: An azaspiro compound that is methoxycyclohexane which is fused at position 4 to the 5-position of a 1,5-dihydro-2H-pyrrol-2-one that is substituted at positions 3 and 4 by 2,5-dimethylphenyl and (ethoxycarbonyl)oxy groups, respectively (the cis isomer). It is a proinsecticide (via hydrolysis of the ethyl carbonate group to give the corresponding 4-hydroxypyrrol-2-one, 'spirotetramat-enol') and is used for the control of a wide range of sucking insects on fruit and potato crops.
Chemical ID: MESH:C570705
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vnn1decreases expressionISOVnn1 (Mus musculus)6480464CTDspirotetramat results in decreased expression of VNN1 mRNAPMID:27917277
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