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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2741
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr3c1
Name: nuclear receptor subfamily 3, group C, member 1
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr3c1decreases methylationEXP 6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in decreased methylation of NR3C1 genePMID:25533936
Nr3c1affects expressionISONR3C1 (Homo sapiens)6480464CTD2,2',4,4'-tetrabromodiphenyl ether affects the expression of NR3C1 mRNAPMID:31173147
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