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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308542
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sirt1
Name: sirtuin 1
Acc ID: CHEBI:81539
Term: metiram
Definition: A polymer comprising ethylenebis(dithiocarbamate) units and (ammonia)zinc(II). It is used in agriculture for the control of scab in fruit, blight in tomatoes and potatoes, and downy mildew in hops and grapes.
Chemical ID: MESH:C008971
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sirt1decreases activityISOSIRT1 (Homo sapiens)6480464CTDpolymarcine results in decreased activity of SIRT1 proteinPMID:21251949
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