Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
2,3',4,4',5-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]; [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]; [AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]
2,3',4,4',5-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYBB mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of LDHA mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of NCF1 mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of NCF4 mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PDK1 mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PKM mRNA]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PKM protein]; AHR protein affects the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA]