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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732856 Species: Mus musculus RGD Object: Gene Symbol: Ilk Name: integrin linked kinase

Acc ID: CHEBI:8093 Term: phenylephrine Definition: A phenylethanolamine that has formula C9H13NO2. CasRN: 59-42-7 Chemical ID: MESH:D010656

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Phenylephrine affects the reaction [ANGPT1 protein results in increased expression of ILK protein]	PMID:18502941
multiple interactions	ISO	RGD:620063	6480464	CTD	ILK protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]	PMID:16170337
affects localization	ISO	RGD:620063	6480464	CTD	Phenylephrine affects the localization of ILK protein	PMID:16170337