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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3615
Species: Rattus norvegicus
RGD Object: Gene
Symbol: S100b
Name: S100 calcium binding protein B
Acc ID: CHEBI:8093
Term: phenylephrine
Definition: A member of the class of the class of phenylethanolamines that is (1R)-2-(methylamino)-1-phenylethan-1-ol carrying an additional hydroxy substituent at position 3 on the phenyl ring.
Chemical ID: MESH:D010656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S100bincreases expressionEXP 6480464CTDPhenylephrine results in increased expression of S100B mRNAPMID:15652358
S100bmultiple interactionsEXP 6480464CTDS100A6 protein inhibits the reaction [Phenylephrine results in increased expression of S100B mRNA]; S100B protein inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]; S100B protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]PMID:15652358
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