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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2201
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bdkrb2
Name: bradykinin receptor B2
Acc ID: CHEBI:8093
Term: phenylephrine
Definition: A member of the class of the class of phenylethanolamines that is (1R)-2-(methylamino)-1-phenylethan-1-ol carrying an additional hydroxy substituent at position 3 on the phenyl ring.
Chemical ID: MESH:D010656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bdkrb2increases expressionEXP 6480464CTDPhenylephrine results in increased expression of BDKRB2 mRNAPMID:18158353
Bdkrb2affects response to substanceISOBdkrb2 (Mus musculus)6480464CTDBDKRB2 affects the susceptibility to PhenylephrinePMID:10614985
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