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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:80828
Term: Gastrodin
Definition: A glycoside that has formula C13H18O7.
Chemical ID: MESH:C045345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relamultiple interactionsEXP 6480464CTDgastrodin inhibits the reaction [3,3'-iminodipropionitrile results in increased phosphorylation of RELA protein]; gastrodin inhibits the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased phosphorylation of RELA protein]PMID:30790395 PMID:31468582
Relamultiple interactionsISORela (Mus musculus)6480464CTDgastrodin promotes the reaction [RELA protein binds to BCL2 promoter]; gastrodin promotes the reaction [RELA protein binds to IL2 promoter]PMID:23578476
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