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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620944
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp7
Name: caspase 7
Acc ID: CHEBI:80774
Term: tauroursodeoxycholic acid
Definition: A bile acid taurine conjugate derived from ursoodeoxycholic acid.
Chemical ID: MESH:C031655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp7multiple interactionsISOCASP7 (Homo sapiens)6480464CTDursodoxicoltaurine inhibits the reaction [SERPINA1 protein mutant form results in increased activity of CASP7 protein]; ursodoxicoltaurine inhibits the reaction [Thapsigargin results in increased activity of CASP7 protein]PMID:12198651 PMID:17559149
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