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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619930
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb11
Name: ATP binding cassette subfamily B member 11
Acc ID: CHEBI:80774
Term: tauroursodeoxycholic acid
Definition: A bile acid taurine conjugate derived from ursoodeoxycholic acid.
Chemical ID: MESH:C031655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb11decreases expressionEXP 6480464CTDursodoxicoltaurine results in decreased expression of ABCB11 mRNAPMID:15885361
Abcb11increases expressionEXP 6480464CTDursodoxicoltaurine results in increased expression of ABCB11 proteinPMID:11672435
Abcb11multiple interactionsEXP 6480464CTDursodoxicoltaurine results in increased expression of and results in increased activity of ABCB11 proteinPMID:12644037
Abcb11multiple interactionsISOAbcb11 (Mus musculus)6480464CTD[ursodoxicoltaurine co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCB11 proteinPMID:36787806
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