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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71028
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adh4
Name: alcohol dehydrogenase 4 (class II), pi polypeptide
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adh4increases expressionEXP 6480464CTDPhenobarbital results in increased expression of ADH4 mRNAPMID:25182419
Adh4affects expressionISOAdh4 (Mus musculus)6480464CTDPhenobarbital affects the expression of ADH4 mRNAPMID:23091169
Adh4decreases expressionISOADH4 (Homo sapiens)6480464CTDPhenobarbital results in decreased expression of ADH4 mRNAPMID:19084549
Adh4increases expressionISOADH4 (Homo sapiens)6480464CTDPhenobarbital results in increased expression of ADH4 proteinPMID:35881160
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