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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631409
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsp90aa1
Name: heat shock protein 90 alpha family class A member 1
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsp90aa1affects expressionEXP 6480464CTDPhenobarbital affects the expression of HSP90AA1 mRNAPMID:19162173 PMID:23273579
Hsp90aa1increases expressionEXP 6480464CTDPhenobarbital results in increased expression of HSP90AA1 mRNAPMID:17381134 PMID:21318169
Hsp90aa1affects expressionISOHsp90aa1 (Mus musculus)6480464CTDPhenobarbital affects the expression of HSP90AA1 mRNAPMID:23091169
Hsp90aa1decreases expressionISOHSP90AA1 (Homo sapiens)6480464CTDPhenobarbital results in decreased expression of HSP90AA1 proteinPMID:35881160
Hsp90aa1increases expressionISOHsp90aa1 (Mus musculus)6480464CTDPhenobarbital results in increased expression of HSP90AA1 proteinPMID:35881160
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