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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61850
Species: Rattus norvegicus
RGD Object: Gene
Symbol: F10
Name: coagulation factor X
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F10decreases expressionEXP 6480464CTDPhenobarbital results in decreased expression of F10 mRNAPMID:17381134
F10multiple interactionsEXP 6480464CTD[Phenobarbital co-treated with Vitamin K 2] results in increased activity of F10 proteinPMID:19952496
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