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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1624095
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c39
Name: cytochrome P450, family 2, subfamily c, polypeptide 39
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c39decreases expressionEXP 6480464CTDPhenobarbital results in decreased expression of CYP2C39 mRNAPMID:23091169
Cyp2c39increases expressionEXP 6480464CTDPhenobarbital results in increased expression of CYP2C39 mRNAPMID:19482888 PMID:20403969
Cyp2c39multiple interactionsEXP 6480464CTDNR1I3 protein affects the reaction [Phenobarbital results in increased expression of CYP2C39 mRNA]PMID:19482888
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