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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307646
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lpin1
Name: lipin 1
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lpin1affects expressionISOLpin1 (Mus musculus)6480464CTDPhenobarbital affects the expression of LPIN1 mRNAPMID:23091169
Lpin1decreases expressionISOLpin1 (Mus musculus)6480464CTDPhenobarbital results in decreased expression of LPIN1 mRNAPMID:19270015 PMID:19850644 PMID:21335049
Lpin1increases expressionISOLpin1 (Mus musculus)6480464CTDPhenobarbital results in increased expression of LPIN1 mRNAPMID:19270015
Lpin1multiple interactionsISOLpin1 (Mus musculus)6480464CTDNR1I3 protein promotes the reaction [Phenobarbital results in decreased expression of LPIN1 mRNA]PMID:19850644
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