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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:8062
Term: phenethyl caffeate
Definition: An alkyl caffeate ester in which 2-phenylethyl is the alkyl component.
Chemical ID: MESH:C055494
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmox1increases expressionEXP 6480464CTDcaffeic acid phenethyl ester results in increased expression of HMOX1 proteinPMID:21472898
Hmox1multiple interactionsEXP 6480464CTDcaffeic acid phenethyl ester inhibits the reaction [Fructose results in increased expression of HMOX1 protein]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of HMOX1 protein]PMID:24508943
Hmox1increases expressionISOHmox1 (Mus musculus)6480464CTDcaffeic acid phenethyl ester results in increased expression of HMOX1 proteinPMID:23942037
Hmox1increases expressionISOHMOX1 (Homo sapiens)6480464CTDcaffeic acid phenethyl ester analog results in increased expression of HMOX1 mRNA; caffeic acid phenethyl ester analog results in increased expression of HMOX1 protein; caffeic acid phenethyl ester results in increased expression of HMOX1 mRNA; caffeic acid phenethyl ester results in increased expression of HMOX1 proteinPMID:20226179 PMID:20950636
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