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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620640
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2d4
Name: cytochrome P450, family 2, subfamily d, polypeptide 4
Acc ID: CHEBI:80579
Term: norcodeine
Definition: A morphinane-like compound that is the N-demethylated derivative of codeine.
Chemical ID: MESH:C010414
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2d4multiple interactionsISOCyp2d22 (Mus musculus)6480464CTD[CYP2D22 protein results in increased metabolism of Codeine] which results in increased chemical synthesis of norcodeinePMID:16595712
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