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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619934
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2c6
Name: cytochrome P450, family 2, subfamily C, polypeptide 6
Acc ID: CHEBI:8050
Term: phenacetin
Definition: A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a 4-ethoxyphenyl group.
Chemical ID: MESH:D010615
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c6affects metabolic processingEXP 6480464CTDCYP2C6V1 protein affects the metabolism of PhenacetinPMID:15231049 PMID:15879494
Cyp2c6decreases ethylationEXP 6480464CTDCYP2C6V1 protein results in decreased ethylation of PhenacetinPMID:11911841
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