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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69051
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfb1
Name: transforming growth factor, beta 1
Acc ID: CHEBI:7986
Term: Pentoxifylline
Definition: An oxopurine that has formula C13H18N4O3.
Chemical ID: MESH:D010431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfb1decreases expressionEXP 6480464CTDPentoxifylline results in decreased expression of TGFB1 mRNAPMID:11788567
Tgfb1multiple interactionsEXP 6480464CTDPentoxifylline inhibits the reaction [Cisplatin results in increased expression of TGFB1 protein]PMID:32777238
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