GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nr1i3 | multiple interactions | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | nonylphenol affects the reaction [NR1I3 affects the susceptibility to Zoxazolamine]; nonylphenol binds to and results in increased activity of NR1I3 protein; nonylphenol inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]; NR1I3 affects the reaction [nonylphenol results in decreased expression of CYP2C40 mRNA]; NR1I3 gene mutant form affects the reaction [nonylphenol results in increased expression of CYP2B10 mRNA]; NR1I3 gene mutant form affects the reaction [nonylphenol results in increased expression of CYP2C29 mRNA]; NR1I3 gene mutant form affects the reaction [nonylphenol results in increased expression of CYP3A11 mRNA] | PMID:18832183 PMID:19041682 | |
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