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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3959
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vdr
Name: vitamin D receptor
Acc ID: CHEBI:7931
Term: paricalcitol
Definition: A seco-cholestane that has formula C27H44O3.
Chemical ID: MESH:C084656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vdraffects bindingISOVDR (Homo sapiens)6480464CTDparicalcitol binds to VDR proteinPMID:15898824
Vdrmultiple interactionsISOVDR (Homo sapiens)6480464CTD[Phosphorus co-treated with paricalcitol] results in increased expression of VDR protein; [Phosphorus co-treated with paricalcitol] results in increased localization of VDR protein; paricalcitol binds to and affects the activity of VDR proteinPMID:16076355 PMID:17715259
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