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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:78886
Term: 2-tert-butylhydroquinone
Definition: A member of the class of hydroquinones in which one of the ring hydrogens of hydroquinone is replaced by a tert-butyl group.
Chemical ID: MESH:C018855
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bmultiple interactionsEXP 6480464CTD2-tert-butylhydroquinone inhibits the reaction [ferrous sulfate results in increased expression of IL1B protein]; 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride, Dietary results in increased expression of and results in increased secretion of IL1B protein]PMID:28583816 PMID:28844481
Il1bmultiple interactionsISOIL1B (Homo sapiens)6480464CTD2-tert-butylhydroquinone inhibits the reaction [IL1B protein affects the localization of NFKBIA protein]; 2-tert-butylhydroquinone inhibits the reaction [IL1B protein affects the localization of RELA protein]; 2-tert-butylhydroquinone inhibits the reaction [IL1B protein results in increased expression of ICAM1 protein]; 2-tert-butylhydroquinone inhibits the reaction [IL1B protein results in increased expression of TNFAIP3 protein]PMID:35724838
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