GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fos | increases expression | EXP | | 6480464 | CTD | pyrrolidine dithiocarbamic acid results in increased expression of FOS mRNA | PMID:7539260 | Fos | increases expression | ISO | FOS (Homo sapiens) | 6480464 | CTD | pyrrolidine dithiocarbamic acid results in increased expression of FOS protein | PMID:17032174 | Fos | multiple interactions | ISO | FOS (Homo sapiens) | 6480464 | CTD | bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of FOS mRNA] | PMID:15477007 PMID:17032174 PMID:7539260 | |
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