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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620525
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mcl1
Name: MCL1 apoptosis regulator, BCL2 family member
Acc ID: CHEBI:78759
Term: N,N-dimethylsphingosine
Definition: A sphingoid that is sphingosine in which the two amino hydrogens are replaced by methyl groups.
Chemical ID: MESH:C061800
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mcl1multiple interactionsISOMCL1 (Homo sapiens)6480464CTD[Bortezomib co-treated with N,N-dimethylsphingosine] results in decreased expression of MCL1 proteinPMID:21195056
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