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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628827
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1d1
Name: nuclear receptor subfamily 1, group D, member 1
Acc ID: CHEBI:77774
Term: SCH-351591
Definition: An aromatic amide resulting from the formal condensation of the carboxy group of 8-methoxy-2-(trifluoromethyl)quinoline-5-carboxylic acid with the primary amino group of 3,5-dichloropyridin-4-amine 1-oxide. It is a potent inhibitor of phosphodiesterase IV (PDE4).
Chemical ID: MESH:C459379
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1d1increases expressionEXP 6480464CTDSCH 351591 results in increased expression of NR1D1 mRNAPMID:20585143
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