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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62387
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdx1
Name: pancreatic and duodenal homeobox 1
Acc ID: CHEBI:77543
Term: ebselen
Definition: A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.
Chemical ID: MESH:C042986
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdx1multiple interactionsISOPdx1 (Mus musculus)6480464CTD[ebselen co-treated with Glucose] results in increased expression of PDX1 proteinPMID:23795780
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