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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620266
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc4
Name: ATP binding cassette subfamily C member 4
Acc ID: CHEBI:77323
Term: ethoxyquin
Definition: A quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6.
Chemical ID: MESH:D005015
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc4increases expressionISOAbcc4 (Mus musculus)6480464CTDEthoxyquin results in increased expression of ABCC4 mRNAPMID:15833929
Abcc4multiple interactionsISOAbcc4 (Mus musculus)6480464CTD[Ethoxyquin results in increased activity of NFE2L2 protein] which results in increased expression of ABCC4 mRNAPMID:15833929
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