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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3763
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sstr2
Name: somatostatin receptor 2
Acc ID: CHEBI:7726
Term: octreotide
Definition: A homodetic cyclic peptide that has formula C49H66N10O10S2.
Chemical ID: MESH:D015282
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sstr2affects response to substanceISOSstr2 (Mus musculus)6480464CTDSSTR2 protein affects the susceptibility to OctreotidePMID:17363388
Sstr2increases activityISOSSTR2 (Homo sapiens)6480464CTD[Octreotide results in increased activity of SSTR2 protein] which results in increased activity of CASP3 proteinPMID:16954443
Sstr2multiple interactionsISOSSTR2 (Homo sapiens)6480464CTD[Octreotide results in increased activity of SSTR2 protein] which results in increased expression of KRT18 protein modified formPMID:16954443
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