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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620353
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc25a5
Name: solute carrier family 25 member 5
Acc ID: CHEBI:77053
Term: closantel
Definition: A racemate comprising equimolar amounts of (R)- and (S)-clostanel. An anthelmintic, it is used (as the dihydrate of the sodium salt) in veterinary medicine for the treatment of fluke and nematode infections.
Chemical ID: MESH:C023342
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc25a5decreases activityISOSLC25A5 (Homo sapiens)6480464CTDclosantel results in decreased activity of SLC25A5 proteinPMID:26746582
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