GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp8 | increases cleavage | ISO | CASP8 (Homo sapiens) | 6480464 | CTD | [methylselenic acid results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; methylselenic acid results in increased cleavage of CASP8 protein | PMID:18790785 | Casp8 | multiple interactions | ISO | CASP8 (Homo sapiens) | 6480464 | CTD | [2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of CASP8 protein; [[methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP9 protein] which results in increased cleavage of CASP8 protein; [methylselenic acid co-treated with Tamoxifen] results in increased cleavage of CASP8 protein | PMID:18444175 PMID:18790785 | |
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