Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70982
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsk3b
Name: glycogen synthase kinase 3 beta
Acc ID: CHEBI:76989
Term: phytoestrogen
Definition: Any compound produced by a plant that happens to have estrogenic activity.
Chemical ID: MESH:D048789
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsk3bincreases phosphorylationEXP 6480464CTDPhytoestrogens results in increased phosphorylation of GSK3B proteinPMID:24726523
Gsk3bmultiple interactionsEXP 6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phytoestrogens results in increased phosphorylation of GSK3B protein]; fulvestrant inhibits the reaction [Phytoestrogens results in increased phosphorylation of GSK3B protein]PMID:24726523
Go Back to source page   Continue to Ontology report