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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708428
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1c3
Name: aldo-keto reductase family 1, member C3
Acc ID: CHEBI:7627
Term: norethisterone
Definition: A 17beta-hydroxy steroid that is testosterone in which the hydrogen at position 17 is replaced by an ethynyl group and in which the methyl group attached to position 10 is replaced by hydrogen.
Chemical ID: MESH:D009640
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1c3decreases activityISOAKR1C3 (Homo sapiens)6480464CTDNorethindrone results in decreased activity of AKR1C3 proteinPMID:21182831
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