GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfe2l2 | multiple interactions | EXP | | 6480464 | CTD | [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Dimethyl Fumarate inhibits the reaction [1,3-dichloro-2-propanol results in decreased expression of NFE2L2 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein] | PMID:36000575 PMID:36999408 | Nfe2l2 | affects localization | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | Dimethyl Fumarate affects the localization of NFE2L2 protein | PMID:27277809 | Nfe2l2 | increases expression | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | Dimethyl Fumarate results in increased expression of NFE2L2 protein | PMID:29950142 | Nfe2l2 | multiple interactions | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTH1 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTL mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTL protein]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein] | PMID:28289076 PMID:28790194 | Nfe2l2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of COX3 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of CYTB mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GSR mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of LAMP2 protein alternative form]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of MTERF1A mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of MTERF3 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of ND1 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of ND2 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of ND5 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of POLG2 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of POLRMT mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of SQSTM1 protein]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of SSBP1 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TFAM mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TFB1M mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TFB2M mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TWNK mRNA]; NFE2L2 protein inhibits the reaction [Dimethyl Fumarate inhibits the reaction [Lipopolysaccharides results in increased abundance of Dinoprostone]]; NFE2L2 protein promotes the reaction [Dimethyl Fumarate inhibits the reaction [Lipopolysaccharides results in increased abundance of Nitrites]] | PMID:23942037 PMID:27277809 PMID:29950142 | | ||||||||||||||||||||||
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