GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gnaq | increases response to substance | ISO | GNAQ (Homo sapiens) | 6480464 | CTD | GNAQ protein mutant form results in increased susceptibility to trametinib | PMID:22733540 | Gnaq | multiple interactions | ISO | GNAQ (Homo sapiens) | 6480464 | CTD | [GNAQ gene mutant form results in increased susceptibility to [trametinib co-treated with omipalisib]] which results in increased cleavage of CASP3 protein; [GNAQ gene mutant form results in increased susceptibility to [trametinib co-treated with omipalisib]] which results in increased cleavage of CASP7 protein; GNAQ gene mutant form results in increased susceptibility to [trametinib co-treated with omipalisib] | PMID:22733540 | | ||||||||||||||||||||||
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