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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2147
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ar
Name: androgen receptor
Acc ID: CHEBI:7590
Term: nitrofen
Definition: An organic molecular entity that has formula C12H7Cl2NO3.
Chemical ID: MESH:C007350
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Araffects bindingISOAR (Homo sapiens)6480464CTDnitrofen binds to AR proteinPMID:15253041
Armultiple interactionsISOAR (Homo sapiens)6480464CTDDihydrotestosterone inhibits the reaction [nitrofen results in increased activity of AR protein]; nitrofen inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; nitrofen inhibits the reaction [Androgens binds to AR protein]; nitrofen inhibits the reaction [Metribolone results in increased activity of AR protein]PMID:15064155 PMID:15253041 PMID:18324785 PMID:33049310
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