GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Drd2 | affects response to substance | EXP | | 6480464 | CTD | DRD2 protein affects the susceptibility to Quinpirole | PMID:12071432 | Drd2 | multiple interactions | EXP | | 6480464 | CTD | [Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine; cypermethrin inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; decamethrin inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]; estradiol 3-benzoate inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; Haloperidol inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; Mirtazapine inhibits the reaction [Quinpirole binds to DRD2 protein]; Nifedipine inhibits the reaction [DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]]; Quinpirole binds to and results in increased activity of DRD2 protein; tautomycin inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine] | PMID:10936494 PMID:11124974 PMID:12523492 PMID:1724532 | Drd2 | increases activity | ISO | DRD2 (Homo sapiens) | 6480464 | CTD | Quinpirole results in increased activity of DRD2 protein | PMID:27920206 | Drd2 | increases response to substance | ISO | Drd2 (Mus musculus) | 6480464 | CTD | DRD2 results in increased susceptibility to Quinpirole | PMID:11790512 | Drd2 | increases response to substance | ISO | DRD2 (Homo sapiens) | 6480464 | CTD | DRD2 protein results in increased susceptibility to Quinpirole | PMID:27920206 | Drd2 | multiple interactions | ISO | Drd2 (Mus musculus) | 6480464 | CTD | DRD2 affects the susceptibility to [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Quinpirole]; DRD2 protein affects the reaction [Quinpirole results in increased phosphorylation of CFL1 protein] | PMID:27717053 PMID:9547254 | Drd2 | multiple interactions | ISO | DRD2 (Homo sapiens) | 6480464 | CTD | [Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; [Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Quinpirole co-treated with DRD2 protein alternative form] results in increased activity of RHOA protein; DRD2 protein promotes the reaction [Quinpirole results in decreased expression of POU5F1 mRNA]; epigallocatechin gallate inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]; JB-788 inhibits the reaction [Quinpirole binds to and results in increased activity of DRD2 protein]; Quinpirole binds to and results in increased activity of DRD2 protein; Sulpiride inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium] | PMID:17958328 PMID:20580787 PMID:27717053 PMID:27920206 PMID:8032591 | |
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