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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:75379
Term: blebbistatin
Definition: A pyrroloquinoline that is 1,2,3,3a-tetrahydro-H-pyrrolo[2,3-b]quinolin-4-one substituted by a hydroxy group at position 3a, a methyl group at position 6 and a phenyl group at position 1. It acts as an inhibitor of ATPase activity of non-muscle myosin II.
Chemical ID: MESH:C472645
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdh1affects localizationISOCDH1 (Homo sapiens)6480464CTDblebbistatin affects the localization of CDH1 proteinPMID:16030252
Cdh1decreases activityISOCDH1 (Homo sapiens)6480464CTDblebbistatin results in decreased activity of CDH1 proteinPMID:16030252
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