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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2581
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Esr1
Name: estrogen receptor 1
Acc ID: CHEBI:75095
Term: chrysin
Definition: A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7.
Chemical ID: MESH:C043561
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr1multiple interactionsISOESR1 (Homo sapiens)6480464CTDchrysin binds to and results in increased activity of ESR1 protein; chrysin promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; chrysin promotes the reaction [ESR1 protein binds to TFF1 promoter]PMID:16972788 PMID:29162470 PMID:33049310 PMID:9751507
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