GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pgr | affects localization | EXP | | 6480464 | CTD | Promegestone affects the localization of PGR protein | PMID:16020483 | Pgr | affects binding | ISO | PGR (Homo sapiens) | 6480464 | CTD | Promegestone binds to PGR protein | PMID:23765520 | Pgr | increases activity | ISO | PGR (Homo sapiens) | 6480464 | CTD | Promegestone results in increased activity of PGR protein | PMID:15103026 PMID:20008677 PMID:30951782 | Pgr | increases uptake | ISO | PGR (Homo sapiens) | 6480464 | CTD | PGR protein results in increased uptake of Promegestone | PMID:21795739 | Pgr | multiple interactions | ISO | Pgr (Mus musculus) | 6480464 | CTD | PGR protein promotes the reaction [Promegestone results in increased expression of FSHB mRNA] | PMID:16675544 | Pgr | multiple interactions | ISO | PGR (Homo sapiens) | 6480464 | CTD | 1,1-bis(4-hydroxyphenyl)cyclohexane inhibits the reaction [Promegestone results in increased activity of PGR protein]; Bortezomib inhibits the reaction [Promegestone results in increased activity of PGR protein]; carfilzomib inhibits the reaction [Promegestone results in increased activity of PGR protein]; Decitabine inhibits the reaction [Promegestone results in increased activity of PGR protein]; fenpyroximate inhibits the reaction [Promegestone results in increased activity of PGR protein]; fluoxastrobin inhibits the reaction [Promegestone results in increased activity of PGR protein]; kresoxim-methyl inhibits the reaction [Promegestone results in increased activity of PGR protein]; methoxyacetic acid promotes the reaction [Promegestone results in increased activity of PGR protein]; metoprine inhibits the reaction [Promegestone results in increased activity of PGR protein]; Mifepristone inhibits the reaction [methoxyacetic acid promotes the reaction [Promegestone results in increased activity of PGR protein]]; picoxystrobin inhibits the reaction [Promegestone results in increased activity of PGR protein]; Proflavine inhibits the reaction [Promegestone results in increased activity of PGR protein]; Promegestone promotes the reaction [ARID1A protein binds to PGR protein]; Promegestone promotes the reaction [SMARCE1 protein binds to PGR protein]; pyrachlostrobin inhibits the reaction [Promegestone results in increased activity of PGR protein]; pyridaben inhibits the reaction [Promegestone results in increased activity of PGR protein]; Rotenone inhibits the reaction [Promegestone results in increased activity of PGR protein]; ST 1481 inhibits the reaction [Promegestone results in increased activity of PGR protein]; trifloxystrobin inhibits the reaction [Promegestone results in increased activity of PGR protein]; U 0126 inhibits the reaction [methoxyacetic acid promotes the reaction [Promegestone results in increased activity of PGR protein]]; Vorinostat inhibits the reaction [Promegestone results in increased activity of PGR protein]; ZNF366 protein inhibits the reaction [Promegestone results in increased activity of PGR protein] | PMID:15103026 PMID:18486176 PMID:19609353 PMID:20008677 PMID:30818834 PMID:30951782 | |
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