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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2626
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fos
Name: Fos proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:73364
Term: 8-OH-DPAT
Definition: A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Chemical ID: MESH:D017371
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosmultiple interactionsEXP 6480464CTD8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Levodopa results in increased expression of FOS protein]PMID:19115412 PMID:19695244
Fosmultiple interactionsISOFos (Mus musculus)6480464CTD8-Hydroxy-2-(di-n-propylamino)tetralin affects the reaction [Haloperidol results in increased expression of FOS protein]PMID:18585397
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