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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552559
Species: Mus musculus
RGD Object: Gene
Symbol: Trpv1
Name: transient receptor potential cation channel, subfamily V, member 1
Acc ID: CHEBI:73224
Term: allyl isothiocyanate
Definition: An isothiocyanate with the formula CH2=CHCH2N=C=S. A colorless oil with boiling point 152degreeC, it is responsible for the pungent taste of mustard, horseradish, and wasabi.
Chemical ID: MESH:C004471
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpv1affects response to substanceEXP 6480464CTDTRPV1 affects the susceptibility to allyl isothiocyanatePMID:21430076
Trpv1increases activityISOTRPV1 (Homo sapiens)6480464CTDallyl isothiocyanate results in increased activity of TRPV1 proteinPMID:29054683
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