GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdk1 | affects phosphorylation | ISO | CDK1 (Homo sapiens) | 6480464 | CTD | temozolomide affects the phosphorylation of CDK1 protein | PMID:23522185 | Cdk1 | increases expression | ISO | CDK1 (Homo sapiens) | 6480464 | CTD | Temozolomide results in increased expression of CDK1 mRNA | PMID:31758290 | Cdk1 | multiple interactions | ISO | CDK1 (Homo sapiens) | 6480464 | CTD | [temozolomide co-treated with resveratrol] results in decreased phosphorylation of CDK1 protein; AKT1 protein inhibits the reaction [temozolomide results in increased phosphorylation of and results in decreased activity of CDK1 protein]; temozolomide results in increased phosphorylation of and results in decreased activity of CDK1 protein | PMID:15930307 PMID:23522185 | |
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