GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Trpv1 | affects binding | EXP | | 6480464 | CTD | capsazepine binds to TRPV1 protein | PMID:15601931 | Trpv1 | decreases activity | EXP | | 6480464 | CTD | capsazepine results in decreased activity of TRPV1 protein | PMID:16446039 PMID:21453681 | Trpv1 | multiple interactions | EXP | | 6480464 | CTD | capsazepine binds to and results in decreased activity of TRPV1 protein; capsazepine inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Cobalt]; capsazepine inhibits the reaction [[Docosahexaenoic Acids co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein modified form]; capsazepine inhibits the reaction [[Eicosapentaenoic Acid co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein modified form]; capsazepine inhibits the reaction [[Formaldehyde results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; capsazepine inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; capsazepine inhibits the reaction [Acrylamide analog inhibits the reaction [Protons results in increased activity of TRPV1 protein]]; capsazepine inhibits the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [benzimidazole analog inhibits the reaction [Protons results in increased activity of TRPV1 protein]]; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [dodecyl sulfate results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Lidocaine results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [N-(4-hydroxyphenyl)arachidonylamide results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [Protons results in increased activity of TRPV1 protein]]; capsazepine inhibits the reaction [resiniferatoxin promotes the reaction [TRPV1 protein binds to TRPV1 protein]]; capsazepine inhibits the reaction [Surface-Active Agents results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [TRPV1 protein results in increased susceptibility to Melitten] | PMID:10822052 PMID:11140687 PMID:11358970 PMID:12922928 PMID:15363968 PMID:15978575 PMID:16135784 PMID:16446039 PMID:16513770 PMID:17038422 PMID:17984664 PMID:18172555 PMID:19540328 PMID:19847360 PMID:21453681 PMID:23264033 | Trpv1 | multiple interactions | ISO | Trpv1 (Mus musculus) | 6480464 | CTD | capsazepine binds to and results in decreased activity of TRPV1 protein; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Olanzapine results in increased expression of TRPV1 mRNA]; TRPV1 protein affects the reaction [capsazepine results in decreased secretion of CALCA protein]; TRPV1 protein affects the susceptibility to [Phenylephrine co-treated with capsazepine] | PMID:12196566 PMID:17082722 PMID:19904815 PMID:21908651 PMID:23747933 PMID:32652086 | Trpv1 | multiple interactions | ISO | TRPV1 (Homo sapiens) | 6480464 | CTD | capsazepine binds to and results in decreased activity of TRPV1 protein; capsazepine inhibits the reaction [[Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; capsazepine inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Cannabidiol results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Citric Acid results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [N-(4-hydroxyphenyl)arachidonylamide binds to and results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Phosphatidylinositol 4,5-Diphosphate affects the reaction [Capsaicin results in increased activity of TRPV1 protein]]; capsazepine inhibits the reaction [Sodium affects the reaction [TRPV1 protein results in increased abundance of Calcium]]; capsazepine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein] | PMID:11278420 PMID:11606325 PMID:12922928 PMID:15363968 PMID:17442041 PMID:18230619 PMID:22566028 PMID:31096838 | |
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