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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3772
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Stat3
Name: signal transducer and activator of transcription 3
Acc ID: CHEBI:7005
Term: morusin
Definition: An extended flavonoid that is flavone substituted by hydroxy groups at positions 5, 2' and 4', a prenyl group at position 3 and a 2,2-dimethyl pyran group across positions 7 and 8.
Chemical ID: MESH:C057451
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stat3decreases phosphorylationISOSTAT3 (Homo sapiens)6480464CTDmorusin results in decreased phosphorylation of STAT3 proteinPMID:25476160
Stat3multiple interactionsISOSTAT3 (Homo sapiens)6480464CTDmorusin results in decreased phosphorylation of and affects the localization of STAT3 proteinPMID:25476160
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