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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:69746
Term: alpinumisoflavone
Definition: An isoflavanone that has formula C20H16O5.
Chemical ID: MESH:C000154
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases cleavageISOCASP3 (Homo sapiens)6480464CTDalpinumisoflavone results in increased cleavage of CASP3 proteinPMID:23850732
Casp3multiple interactionsISOCASP3 (Homo sapiens)6480464CTD[alpinumisoflavone results in increased expression of FAS protein] which results in increased cleavage of CASP3 proteinPMID:23850732
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