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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621414
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnh2
Name: potassium voltage-gated channel subfamily H member 2
Acc ID: CHEBI:6956
Term: Mitragynine
Definition: A monoterpenoid indole alkaloid that has formula C23H30N2O4.
Chemical ID: MESH:C001801
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnh2decreases expressionISOKCNH2 (Homo sapiens)6480464CTDmitragynine results in decreased expression of KCNH2 proteinPMID:27260674
Kcnh2multiple interactionsISOKCNH2 (Homo sapiens)6480464CTDmitragynine binds to and results in decreased activity of KCNH2 proteinPMID:27260674
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